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Table 1 Reduced Mean Corpuscular Volume (MCV) and Heterozygous β-Thalassaemia in 1014 Psychiatric Outpatients

From: Heterozygous β-thalassaemia as a susceptibility factor in mood disorders: excessive prevalence in bipolar patients

RDC Diagnosis Number of Patients MCV<80 μ3 N (%) Heterozygous β-Thalassaemiaa
    Definite Probable Total (%)
Manic Schizoaffective 288 88 (30.6) 42 16 58 (20.1)
Bipolar with Mania 269 59 (21.9) 17 21 38 (14.1)
Bipolar with Hypomania 175 36 (20.6) 16 8 24 (13.7)
Depressive Schizoaffective 96 19 (19.8) 6 4 10 (10.4)
Recurrent Major Depression 124 24 (19.4) 7 7 14 (11.3)
Other (Schizophrenia, Minor Depression, etc) 62 8 (12.9) 1 3 4 (6.5)
TOTAL 1014 234 (23.1) 89 59 148 (14.6)
  1. aRates of heterozygous β-thalassaemia are estimated based on the number of definite cases (MCV <80 μ3 and increased HbA2) plus the number of probable cases (62 % of patients with MCV <80 μ3 but unknown HbA2).