Table 2 Mean dosage of antipsychotics according to co-prescription of antiparkinsonians (univariate analysis)
From: Antipsychotics dosage and antiparkinsonian prescriptions
All prescriptions (n = 5712) | Prescriptions with no antiparkinsonian (n = 4148) | Prescriptions with antiparkinsonian (n = 1564) | Comparisons of means | ||||||
|---|---|---|---|---|---|---|---|---|---|
n | Mean dosage mg (chlorpromazine equivalents) [CI95%] | Range of dosage Median (min-max) | n | Mean dosage | n | Mean dosage | t | p | |
olanzapine | 1278 | 10,9 (218) [10,6–11,3] | 10 (5–30) | 1104 | 10,7 | 174 | 11,3 | 0,84 | 0,4 |
risperidone | 713 | 3,5 (175) [3,3–3,7] | 4 (0,5–12) | 590 | 3,2 | 123 | 5,3 | 7,8 | <0,0001 |
amisulpride | 967 | 365 (243) [346–382] | 200 (50–1200) | 627 | 298 | 340 | 468,2 | 10,1 | <0,0001 |
clozapine | 44 | 90,6 (181) [75,8–115,5] | 75 (12,5–450) | 41 | 89,9 | 3 | 100,0 | 0,8 | 0,05 |
haloperidol | 452 | 6,6 (330) [6,1–7,2] | 5 (0,1–30) | 173 | 3,9 | 279 | 8,4 | 68,9 | <0,0001 |