Clinical Practice and Epidemiology in Mental Health

Table 3 Mean CGI-BP scores before and after addition of quetiapine

From: Quetiapine as add-on treatment for bipolar I disorder: efficacy in preventing relapse of depressive episodes

		CGI-BP Score (Mean ± SD)
Observation period	N	Baseline*	During observation	F-ratio	P-value^†
3 months before quetiapine	61	4.5 ± 1.1	4.3 ± 1.4
6 months after quetiapine	61	4.5 ± 1.1	3.4 ± 1.1	30.5	<0.001
12 months after quetiapine	47	4.7 ± 1.0	3.3 ± 1.3	34.3	<0.001
18 months after quetiapine	24	4.8 ± 0.9	3.6 ± 1.0	19.1	<0.001
24 months after quetiapine	14	4.4 ± 0.9	3.0 ± 0.9	16.9	<0.001

*Represents the start of quetiapine treatment except for the observation period at 3 months before the start of quetiapine treatment
^†Observation period versus baseline

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