Table 7 Relationship between depression and subsequent cancer: summary of the review results
From: A meta-analysis on depression and subsequent cancer risk
Number of studies | Summary relative risk (95% CI) | Heterogeneity (I2) | |
|---|---|---|---|
Overall cancer | |||
Crude | 8 | 1.19 (1.06–1.32) | <0.01 |
Multivariate | 7 | 1.12 (0.99–1.26) | <0.01 |
Studies adjusting for smoking | 4 | 1.20 (0.97–1.49) | 0.23 |
Studies with follow-up > 10 years | 6 | 1.08 (0.96–1.22) | <0.01 |
Breast cancer | |||
Crude | 7 | 1.46 (0.80–2.64) | 0.37 |
Multivariate | 8 | 1.59 (0.74–3.44) | 0.37 |
Studies adjusting for smoking | 2 | 1.72 (0.33–9.01) | 0.88 |
Studies with follow-up > 10 years | 5 | 2.50 (1.06–5.91) | 0.74 |
Lung cancer | |||
Crude | 4 | 1.40 (0.90–2.17) | <0.01 |
Multivariate | 4 | 1.37 (0.88–2.16) | <0.01 |
Studies adjusting for smoking | 2 | 1.67 (0.50–5.38) | <0.01 |
Studies with follow-up > 10 years | 3 | 1.31 (082–2.11) | <0.01 |
Prostate cancer (adjusted) | 3 | 1.60 (0.40–6.50) | 0.55 |