Table 1 Demographic and clinical characteristics of patients
From: Combining an SSRI with an anticonvulsant in depressed patients with dysphoric mood: an open study
Gender | Â | 12 males (34%) 23 females (66%) |
Age (mean ± SD) |  | 44.6 ± 11.7 |
Main diagnosis | Â | Major Depressive Disorder 27 (77%) Dysthymic Disorder 4 (11%) Depressive Disorder NOS 3 (9%) Adjustment Disorder with Depressed Mood 1 (3%) |
Psychiatric comorbidity | Â | No comorbid axis I or II disorder 27 (77%) Panic Disorder 2 (6%) Generalised Anxiety Disorder 1 (3%) Bulimia Nervosa 1 (3%) Eating Disorder NOS 1 (3%) Conversion Disorder 1 (3%) Histrionic Personality Disorder 1 (3%) Dependent Personality Disorder 1 (3%) |
HDRS baseline score (mean ± SD) |  | 17.3 ± 3.3 |
Antidepressant drug prescribed | Paroxetine | 11 (31%) (mean dose 24 mg/die, range 20–30) |
|  | Fluvoxamine | 10 (29%) (mean dose 125 mg/die, range 100–250) |
|  | Citalopram | 10 (29%) (mean dose 29 mg/die, range 20–40) |
| Â | Fluoxetine | 2 (6%) (both patients on 20 mg/die) |
|  | Sertraline | 2 (6%) (mean dose 125 mg/die, range 100–150) |
Anticonvulsant prescribed | Valproate | 26 (74%) (mean dose 438 mg/die, range 200–1000) |
|  | Carbamazepine | 3 (9%) (mean dose 550 mg/die, range 450–600) |
|  | Gabapentin | 6 (17%) (mean dose 517 mg/die, range 300–600) |