Table 2 Changes in outcome measures over time
From: Combining an SSRI with an anticonvulsant in depressed patients with dysphoric mood: an open study
Outcome measure | Baseline (mean ± SD) | 4 weeks (mean ± SD) | 12 weeks (mean ± SD) |
|---|---|---|---|
HDRS total score* | 17.3 ± 3.3 (n = 35) | 12.9 ± 3.7 (n = 32) | 9.3 ± 3.9 (n = 20) |
HDRS Core depression factor* | 4.8 ± 1.4 (n = 35) | 3.4 ± 1.5 (n = 32) | 2.1 ± 1.3 (n = 20) |
HDRS Anxiety factor* | 3.6 ± 1.5 (n = 35) | 3.1 ± 1.3 (n = 32) | 2.3 ± 1.0 (n = 20) |
SVARAD Core depression factor* | 3.5 ± 1.2 (n = 35) | 2.2 ± 1.2 (n = 32) | 1.1 ± 1.0 (n = 23) |
SVARAD Anxiety factor* | 3.1 ± 1.3 (n = 35) | 2.4 ± 1.2 (n = 32) | 2.0 ± 1.5 (n = 23) |
SVARAD Anger/irritability factor* | 3.2 ± 1.5 (n = 35) | 1.7 ± 1.2 (n = 32) | 1.0 ± 0.8 (n = 23) |